One of Diane Haddad's readers received several boxes of family genealogy research that she had to do something with. On her Blog Genealogy Insider she asked her readers for suggestions.
We may not all be faced with a task this daunting, but the suggestions she received are worth looking at. There are organizational ideas that all of us could use, if not in total, then at least in part.
You can read her summary of some of the suggestions at: Genealogy Insider - Your Advice for Organizing Family Archives